AP-2-Associated Protein Kinase 1 and Cyclin G-Associated Kinase Regulate Hepatitis C Virus Entry and Are Potential Drug Targets

Hepatitis C virus (HCV) enters its target cell via clathrin-mediated endocytosis. AP-2-associated protein kinase 1 (AAK1) and cyclin G-associated kinase (GAK) are host kinases that regulate clathrin adaptor protein (AP)-mediated trafficking in the endocytic and secretory pathways. We previously repo...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Neveu, Gregory, Ziv-Av, Amotz, Barouch-Bentov, Rina, Berkerman, Elena, Mulholland, Jon, Einav, Shirit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442395/
https://ncbi.nlm.nih.gov/pubmed/25653444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02705-14
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