Identification and Targeting of an Interaction between a Tyrosine Motif within Hepatitis C Virus Core Protein and AP2M1 Essential for Viral Assembly

Novel therapies are urgently needed against hepatitis C virus infection (HCV), a major global health problem. The current model of infectious virus production suggests that HCV virions are assembled on or near the surface of lipid droplets, acquire their envelope at the ER, and egress through the se...

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Bibliographic Details
Main Authors: Neveu, Gregory, Barouch-Bentov, Rina, Ziv-Av, Amotz, Gerber, Doron, Jacob, Yves, Einav, Shirit
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420927/
https://ncbi.nlm.nih.gov/pubmed/22916011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002845
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