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HIV-1 Fitness Cost Associated with Escape from the VRC01 Class of CD4 Binding Site Neutralizing Antibodies

Broadly neutralizing antibodies (bNAbs) have been isolated from selected HIV-1-infected individuals and shown to bind to conserved sites on the envelope glycoprotein (Env). However, circulating plasma virus in these donors is usually resistant to autologous isolated bNAbs, indicating that during chr...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Lynch, Rebecca M., Wong, Patrick, Tran, Lillian, O'Dell, Sijy, Nason, Martha C., Li, Yuxing, Wu, Xueling, Mascola, John R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442379/
https://ncbi.nlm.nih.gov/pubmed/25631091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03608-14
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