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Determining the specificities of TALENs, Cas9, and other genome editing enzymes

The rapid development of programmable site-specific endonucleases has led to a dramatic increase in genome engineering activities for research and therapeutic purposes. Specific loci of interest in the genomes of a wide range of organisms including mammals can now be modified using zinc-finger nucle...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Pattanayak, Vikram, Guilinger, John P., Liu, David R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440668/
https://ncbi.nlm.nih.gov/pubmed/25398335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-801185-0.00003-9
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