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Genome Editing with mRNA Encoding ZFN, TALEN, and Cas9

Genome-editing technologies based on programmable nucleases have significantly broadened our ability to make precise and direct changes in the genomic DNA of various species, including human cells. Delivery of programmable nucleases into the target tissue or cell is one of the pressing challenges in...

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Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Zhang, Hong-Xia, Zhang, Ying, Yin, Hao
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453514/
https://ncbi.nlm.nih.gov/pubmed/30803822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.01.014
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