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Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing

Our ability to precisely and efficiently edit mammalian and plant genomes has been significantly improved in recent years, partially due to increasing use of designer nucleases that recognize a pre-determined DNA sequence, make a specific DNA double-strand break, and stimulate gene targeting. A pair...

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Detalhes bibliográficos
Main Authors: Yan, Wei, Smith, Cory, Cheng, Linzhao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736171/
https://ncbi.nlm.nih.gov/pubmed/23921522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02376
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