Diurnal and stress‐induced intra‐hippocampal corticosterone rise attenuated in 11β‐HSD1‐deficient mice: a microdialysis study in young and aged mice

11β‐Hydroxysteroid dehydrogenase type 1 (11β‐HSD1) locally regenerates active glucocorticoids from their inert forms thereby amplifying intracellular levels within target tissues including the brain. We previously showed greater increases in intra‐hippocampal corticosterone (CORT) levels upon Y‐maze...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Yau, Joyce L. W., Noble, June, Kenyon, Christopher J., Ludwig, Mike, Seckl, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Behavioral Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440343/
https://ncbi.nlm.nih.gov/pubmed/25614240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12836
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