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Prolonged survival of a patient with metastatic leptomeningeal melanoma treated with BRAF inhibition-based therapy: a case report

BACKGROUND: Leptomeningeal metastasis of melanoma is a devastating complication with a grave prognosis, and there are no known effective standard treatments. Although selective BRAF inhibitors have demonstrated a significant clinical activity in patients with metastatic melanoma harboring a BRAF mut...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Kim, Dae Won, Barcena, Edelyn, Mehta, Urvi N, Rohlfs, Michelle L, Kumar, Ashok J, Penas-Prado, Marta, Kim, Kevin B
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440312/
https://ncbi.nlm.nih.gov/pubmed/25962795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1391-x
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