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The mTOR inhibitor sirolimus suppresses renal, hepatic, and cardiac tissue cellular respiration

The purpose of this in vitro study was to develop a useful biomarker (e.g., cellular respiration, or mitochondrial O(2) consumption) for measuring activities of mTOR inhibitors. It measured the effects of commonly used immunosuppressants (sirolimus-rapamycin, tacrolimus, and cyclosporine) on cellula...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Albawardi, Alia, Almarzooqi, Saeeda, Saraswathiamma, Dhanya, Abdul-Kader, Hidaya Mohammed, Souid, Abdul-Kader, Alfazari, Ali S
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440113/
https://ncbi.nlm.nih.gov/pubmed/26045804
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