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The mTOR inhibitor sirolimus suppresses renal, hepatic, and cardiac tissue cellular respiration
The purpose of this in vitro study was to develop a useful biomarker (e.g., cellular respiration, or mitochondrial O2 consumption) for measuring activities of mTOR inhibitors. It measured the effects of commonly used immunosuppressants (sirolimus - rapamycin, tacrolimus, and cyclosporine) on cellula...
Gardado en:
| Publicado en: | Int J Physiol Pathophysiol Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
e-Century Publishing Corporation
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4446389/ https://ncbi.nlm.nih.gov/pubmed/26069529 |
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