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The mTOR inhibitor sirolimus suppresses renal, hepatic, and cardiac tissue cellular respiration
The purpose of this in vitro study was to develop a useful biomarker (e.g., cellular respiration, or mitochondrial O2 consumption) for measuring activities of mTOR inhibitors. It measured the effects of commonly used immunosuppressants (sirolimus - rapamycin, tacrolimus, and cyclosporine) on cellula...
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| Publié dans: | Int J Physiol Pathophysiol Pharmacol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
e-Century Publishing Corporation
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4446389/ https://ncbi.nlm.nih.gov/pubmed/26069529 |
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