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The mTOR inhibitor sirolimus suppresses renal, hepatic, and cardiac tissue cellular respiration

The purpose of this in vitro study was to develop a useful biomarker (e.g., cellular respiration, or mitochondrial O2 consumption) for measuring activities of mTOR inhibitors. It measured the effects of commonly used immunosuppressants (sirolimus - rapamycin, tacrolimus, and cyclosporine) on cellula...

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Bibliografische gegevens
Gepubliceerd in:Int J Physiol Pathophysiol Pharmacol
Hoofdauteurs: Albawardi, Alia, Almarzooqi, Saeeda, Saraswathiamma, Dhanya, Abdul-Kader, Hidaya Mohammed, Souid, Abdul-Kader, Alfazari, Ali S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446389/
https://ncbi.nlm.nih.gov/pubmed/26069529
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