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In vitro assessment of antitumor activities of the PI3K/mTOR inhibitor GSK2126458
BACKGROUND: Up-regulation of the PI3K/mTOR (phosphatidylinositol-3′ kinase/mammalian target of rapamycin) signaling is common in carcinoma. Consistently, targeting these molecules has been shown to halt the growth of many tumors. The main purpose of this study was to develop surrogate biomarkers of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4189195/ https://ncbi.nlm.nih.gov/pubmed/25298748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0090-z |
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