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In vitro assessment of antitumor activities of the PI3K/mTOR inhibitor GSK2126458

BACKGROUND: Up-regulation of the PI3K/mTOR (phosphatidylinositol-3′ kinase/mammalian target of rapamycin) signaling is common in carcinoma. Consistently, targeting these molecules has been shown to halt the growth of many tumors. The main purpose of this study was to develop surrogate biomarkers of...

詳細記述

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書誌詳細
主要な著者: Albawardi, Alia, Al Ayyan, Muna, Al Bashir, Mohamed, Souid, Abdul-Kader, Almarzooqi, Saeeda
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189195/
https://ncbi.nlm.nih.gov/pubmed/25298748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0090-z
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