Combination of metformin and valproic acid synergistically induces cell cycle arrest and apoptosis in clear cell renal cell carcinoma

Objective: To investigate the antitumor activity of metformin combined with valproic acid (VPA) on renal cell carcinoma (RCC) cell lines. Methods: The effects of metformin combined with VPA on the viability of 786-O and caki-2 cell lines were evaluated by MTT assay. The inhibitory effect of combinat...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Clin Exp Pathol
Egile Nagusiak: Zhang, Xiaolong, Zhang, Xiaopeng, Huang, Tianbao, Geng, Jiang, Liu, Min, Zheng, Junhua
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: e-Century Publishing Corporation 2015
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440099/
https://ncbi.nlm.nih.gov/pubmed/26045790
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