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Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells

BACKGROUND: Metformin is a widely used biguanide drug for the treatment of type 2 diabetes. It has been revaluated as a potential anti-cancer drug with promising activity in various tumors. However, the precise mechanisms underlying the suppression of cancer cells by metformin remain not well unders...

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Опубликовано в: :Med Sci Monit
Главные авторы: Xie, Wei, Wang, Lei, Sheng, Halei, Qiu, Jing, Zhang, Di, Zhang, Le, Yang, Fan, Tang, Dahai, Zhang, Kebin
Формат: Artigo
Язык:Inglês
Опубликовано: International Scientific Literature, Inc. 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226302/
https://ncbi.nlm.nih.gov/pubmed/28045889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.898710
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