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Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells
BACKGROUND: Metformin is a widely used biguanide drug for the treatment of type 2 diabetes. It has been revaluated as a potential anti-cancer drug with promising activity in various tumors. However, the precise mechanisms underlying the suppression of cancer cells by metformin remain not well unders...
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Publié dans: | Med Sci Monit |
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Auteurs principaux: | , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
International Scientific Literature, Inc.
2017
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5226302/ https://ncbi.nlm.nih.gov/pubmed/28045889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.898710 |
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