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Combined Treatment with Valproic Acid and 5-Aza-2′-Deoxycytidine Synergistically Inhibits Human Clear Cell Renal Cell Carcinoma Growth and Migration
BACKGROUND: Histone acetylation and DNA methylation are important mammalian epigenetic modifications that participate in the regulation of gene expression. Because dysregulation of histone deacetylase and DNA methyltransferases are hallmarks of malignancy, they have become promising therapeutic targ...
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| Publicado no: | Med Sci Monit |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Scientific Literature, Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5827631/ https://ncbi.nlm.nih.gov/pubmed/29457966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.906020 |
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