Phase 1/2 study of the combination of 5-aza-2′-deoxycytidine with valproic acid in patients with leukemia

We conducted a phase 1/2 study of the combination of 5-aza-2′-deoxycytidine (decitabine) and the histone deacetylase inhibitor valproic acid (VPA) in patients with advanced leukemia, including older untreated patients. A group of 54 patients were treated with a fixed dose of decitabine (15 mg/m(2) b...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Garcia-Manero, Guillermo, Kantarjian, Hagop M., Sanchez-Gonzalez, Blanca, Yang, Hui, Rosner, Gary, Verstovsek, Srdan, Rytting, Michael, Wierda, William G., Ravandi, Farhad, Koller, Charles, Xiao, Lianchun, Faderl, Stefan, Estrov, Zeev, Cortes, Jorge, O'Brien, Susan, Estey, Elihu, Bueso-Ramos, Carlos, Fiorentino, Jackie, Jabbour, Elias, Issa, Jean-Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Hematology 2006
Soggetti:
Clinical Trials and Observations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895437/
https://ncbi.nlm.nih.gov/pubmed/16882711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-009142
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi