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Metformin Induces Cell Cycle Arrest and Apoptosis in Drug-Resistant Leukemia Cells

Recent epidemiological studies indicate that the antidiabetic drug metformin has chemosensitizing and chemopreventive effects against carcinogenesis. Here, we demonstrate that metformin exerts varying degrees of antitumor activity against human leukemia cells, as reflected by differences in growth i...

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Detalhes bibliográficos
Publicado no:Leuk Res Treatment
Main Authors: Rodríguez-Lirio, A., Pérez-Yarza, G., Fernández-Suárez, M. R., Alonso-Tejerina, E., Boyano, M. D., Asumendi, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673355/
https://ncbi.nlm.nih.gov/pubmed/26688757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/516460
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