Metformin Induces Cell Cycle Arrest and Apoptosis in Drug-Resistant Leukemia Cells

Recent epidemiological studies indicate that the antidiabetic drug metformin has chemosensitizing and chemopreventive effects against carcinogenesis. Here, we demonstrate that metformin exerts varying degrees of antitumor activity against human leukemia cells, as reflected by differences in growth i...

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Bibliografiske detaljer
Udgivet i:Leuk Res Treatment
Main Authors: Rodríguez-Lirio, A., Pérez-Yarza, G., Fernández-Suárez, M. R., Alonso-Tejerina, E., Boyano, M. D., Asumendi, A.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673355/
https://ncbi.nlm.nih.gov/pubmed/26688757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/516460
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