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Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency
Generation of induced pluripotent stem cells (iPSCs) is a process whose mechanistic underpinnings are only beginning to emerge. Here, we applied in-depth quantitative proteomics to monitor proteome changes during the course of reprogramming of fibroblasts to iPSCs. We uncover a 2-step resetting of t...
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| Veröffentlicht in: | Cell Rep |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4438680/ https://ncbi.nlm.nih.gov/pubmed/23260666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.10.014 |
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