Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency

Generation of induced pluripotent stem cells (iPSCs) is a process whose mechanistic underpinnings are only beginning to emerge. Here, we applied in-depth quantitative proteomics to monitor proteome changes during the course of reprogramming of fibroblasts to iPSCs. We uncover a 2-step resetting of t...

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Publicat a:Cell Rep
Autors principals: Hansson, Jenny, Rafiee, Mahmoud Reza, Reiland, Sonja, Polo, Jose M., Gehring, Julian, Okawa, Satoshi, Huber, Wolfgang, Hochedlinger, Konrad, Krijgsveld, Jeroen
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438680/
https://ncbi.nlm.nih.gov/pubmed/23260666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.10.014
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