Impaired Th17 polarization of phenotypically naive CD4(+) T-cells during chronic HIV-1 infection and potential restoration with early ART

BACKGROUND: Depletion of mucosal Th17 cells during HIV/SIV infections is a major cause for microbial translocation, chronic immune activation, and disease progression. Mechanisms contributing to Th17 deficit are not fully elucidated. Here we investigated alterations in the Th17 polarization potentia...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Retrovirology
मुख्य लेखकों: DaFonseca, Sandrina, Niessl, Julia, Pouvreau, Sylvia, Wacleche, Vanessa Sue, Gosselin, Annie, Cleret-Buhot, Aurélie, Bernard, Nicole, Tremblay, Cécile, Jenabian, Mohammad-Ali, Routy, Jean-Pierre, Ancuta, Petronela
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438463/
https://ncbi.nlm.nih.gov/pubmed/25924895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0164-6
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