Impaired Th17 polarization of phenotypically naive CD4(+) T-cells during chronic HIV-1 infection and potential restoration with early ART

BACKGROUND: Depletion of mucosal Th17 cells during HIV/SIV infections is a major cause for microbial translocation, chronic immune activation, and disease progression. Mechanisms contributing to Th17 deficit are not fully elucidated. Here we investigated alterations in the Th17 polarization potentia...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Retrovirology
Hlavní autoři: DaFonseca, Sandrina, Niessl, Julia, Pouvreau, Sylvia, Wacleche, Vanessa Sue, Gosselin, Annie, Cleret-Buhot, Aurélie, Bernard, Nicole, Tremblay, Cécile, Jenabian, Mohammad-Ali, Routy, Jean-Pierre, Ancuta, Petronela
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438463/
https://ncbi.nlm.nih.gov/pubmed/25924895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0164-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky