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High glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression

High glucose milieu inhibits PTEN expression to activate Akt kinase and induces glomerular mesangial cell hypertrophy and matrix protein expression in diabetic nephropathy. Specific mechanism by which high glucose inhibits PTEN expression is not clear. We found that high glucose increased the expres...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Signal
Asıl Yazarlar: Dey, Nirmalya, Bera, Amit, Das, Falguni, Ghosh-Choudhury, Nandini, Kasinath, Balakuntalam S., Choudhury, Goutam Ghosh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437875/
https://ncbi.nlm.nih.gov/pubmed/25797045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.03.007
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