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Trapping the dynamic acyl carrier protein in fatty acid biosynthesis

Acyl carrier protein (ACP) transports the growing fatty acid chain between enzyme domains of fatty acid synthase (FAS) during biosynthesis.(1) Because FAS enzymes operate upon ACP-bound acyl groups, ACP must stabilize and transport the growing lipid chain.(2) The transient nature of ACP-enzyme inter...

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Bibliographische Detailangaben
Veröffentlicht in:Nature
Hauptverfasser: Nguyen, Chi, Haushalter, Robert W., Lee, D. John, Markwick, Phineus R. L., Bruegger, Joel, Caldara-Festin, Grace, Finzel, Kara, Jackson, David R., Ishikawa, Fumihiro, O’Dowd, Bing, McCammon, J. Andrew, Opella, Stanley J., Tsai, Shiou-Chuan, Burkart, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437705/
https://ncbi.nlm.nih.gov/pubmed/24362570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12810
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