Trapping the dynamic acyl carrier protein in fatty acid biosynthesis

Acyl carrier protein (ACP) transports the growing fatty acid chain between enzyme domains of fatty acid synthase (FAS) during biosynthesis.(1) Because FAS enzymes operate upon ACP-bound acyl groups, ACP must stabilize and transport the growing lipid chain.(2) The transient nature of ACP-enzyme inter...

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Publicat a:Nature
Autors principals: Nguyen, Chi, Haushalter, Robert W., Lee, D. John, Markwick, Phineus R. L., Bruegger, Joel, Caldara-Festin, Grace, Finzel, Kara, Jackson, David R., Ishikawa, Fumihiro, O’Dowd, Bing, McCammon, J. Andrew, Opella, Stanley J., Tsai, Shiou-Chuan, Burkart, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437705/
https://ncbi.nlm.nih.gov/pubmed/24362570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12810
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