Mechanism of Scrapie Prion Precipitation with Phosphotungstate Anions

[Image: see text] The phosphotungstate anion (PTA) is widely used to facilitate the precipitation of disease-causing prion protein (PrP(Sc)) from infected tissue for applications in structural studies and diagnostic approaches. However, the mechanism of this precipitation is not understood. In order...

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Vydáno v:ACS Chem Biol
Hlavní autoři: Levine, Dana J., Stöhr, Jan, Falese, Lillian E., Ollesch, Julian, Wille, Holger, Prusiner, Stanley B., Long, Jeffrey R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437617/
https://ncbi.nlm.nih.gov/pubmed/25695325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5006239
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