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A novel HSP90 inhibitor delays castrate resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis

PURPOSE: Prostate cancer responds initially to anti-androgen therapies, however, progression to castration resistant disease frequently occurs. Therefore there is an urgent need for novel therapeutic agents that can prevent the emergence of castration resistant prostate cancer (CRPC). Hsp90 is a mol...

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書目詳細資料
發表在:Clin Cancer Res
Main Authors: Lamoureux, Francois, Thomas, Christian, Yin, Min-Jean, Kuruma, Hidetoshi, Fazli, Ladan, Gleave, Martin E, Zoubeidi, Amina
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437585/
https://ncbi.nlm.nih.gov/pubmed/21349995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3077
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