A novel HSP90 inhibitor delays castrate resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis

Lignende værker

• Suppression of Heat Shock Protein 27 Using OGX-427 Induces Endoplasmic Reticulum Stress and Potentiates Heat Shock Protein 90 Inhibitors to Delay Castrate-resistant Prostate Cancer
  af: Lamoureux, François, et al.
  Udgivet: (2013)
• Hsp27 promotes IGF-1 survival signaling in prostate cancer via p90Rsk-dependent phosphorylation and inactivation of BAD
  af: Zoubeidi, Amina, et al.
  Udgivet: (2010)
• Dual inhibition of autophagy and the AKT pathway in prostate cancer
  af: Lamoureux, Francois, et al.
  Udgivet: (2013)
• Inhibition of the HER2-YB1-AR axis with Lapatinib synergistically enhances Enzalutamide anti-tumor efficacy in castration resistant prostate cancer
  af: Shiota, Masaki, et al.
  Udgivet: (2015)
• Co-targeting stress-activated Hsp27 and autophagy as a combinatorial strategy to amplify endoplasmic reticular stress in prostate cancer
  af: Kumano, Masafumi, et al.
  Udgivet: (2012)