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Dual inhibition of autophagy and the AKT pathway in prostate cancer
Genetic inactivation of PTEN through either gene deletion or mutation is common in metastatic prostate cancer, leading to activation of the phosphoinositide 3-kinase (PI3K-AKT) pathway, which is associated with poor clinical outcomes. The PI3K-AKT pathway plays a central role in various cellular pro...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3722327/ https://ncbi.nlm.nih.gov/pubmed/23670050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24921 |
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