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Inhibition of Hsp90 Augments Docetaxel Therapy in Castrate Resistant Prostate Cancer

First line treatment of patients with castrate resistant prostate cancer (CRPC) primarily involves administration of docetaxel chemotherapy. Unfortunately, resistance to docetaxel therapy is an ultimate occurrence. Alterations in androgen receptor (AR) expression and signaling are associated mechani...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ku, ShengYu, Lasorsa, Elena, Adelaiye, Remi, Ramakrishnan, Swathi, Ellis, Leigh, Pili, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114978/
https://ncbi.nlm.nih.gov/pubmed/25072314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103680
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