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The role of molecular chaperones in clathrin mediated vesicular trafficking

The discovery that the 70 kD “uncoating ATPase,” which removes clathrin coats from vesicles after endocytosis, is the constitutively expressed Hsc70 chaperone was a surprise. Subsequent work, however, revealed that uncoating is an archetypal Hsp70 reaction: the cochaperone auxilin, which contains a...

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Bibliografiske detaljer
Udgivet i:Front Mol Biosci
Main Authors: Sousa, Rui, Lafer, Eileen M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436892/
https://ncbi.nlm.nih.gov/pubmed/26042225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00026
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