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The role of molecular chaperones in clathrin mediated vesicular trafficking

The discovery that the 70 kD “uncoating ATPase,” which removes clathrin coats from vesicles after endocytosis, is the constitutively expressed Hsc70 chaperone was a surprise. Subsequent work, however, revealed that uncoating is an archetypal Hsp70 reaction: the cochaperone auxilin, which contains a...

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Vydáno v:Front Mol Biosci
Hlavní autoři: Sousa, Rui, Lafer, Eileen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436892/
https://ncbi.nlm.nih.gov/pubmed/26042225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00026
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