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Structural mechanisms of chaperone mediated protein disaggregation

The ClpB/Hsp104 and Hsp70 classes of molecular chaperones use ATP hydrolysis to dissociate protein aggregates and complexes, and to move proteins through membranes. ClpB/Hsp104 are members of the AAA+ family of proteins which form ring-shaped hexamers. Loops lining the pore in the ring engage substr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Mol Biosci
Egile nagusia: Sousa, Rui
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428496/
https://ncbi.nlm.nih.gov/pubmed/25988153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2014.00012
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