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Structural mechanisms of chaperone mediated protein disaggregation
The ClpB/Hsp104 and Hsp70 classes of molecular chaperones use ATP hydrolysis to dissociate protein aggregates and complexes, and to move proteins through membranes. ClpB/Hsp104 are members of the AAA+ family of proteins which form ring-shaped hexamers. Loops lining the pore in the ring engage substr...
Enregistré dans:
| Publié dans: | Front Mol Biosci |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4428496/ https://ncbi.nlm.nih.gov/pubmed/25988153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2014.00012 |
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