Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction

Objectives. Low survival rate of mesenchymal stem cells (MSCs) severely limited the therapeutic efficacy of cell therapy in the treatment of myocardial infarction (MI). Bcl-xL genetic modification might enhance MSC survival after transplantation. Methods. Adult rat bone marrow MSCs were modified wit...

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Bibliografski detalji
Izdano u:Stem Cells Int
Glavni autori: Xue, Xiaodong, Liu, Yu, Zhang, Jian, Liu, Tao, Yang, Zhonglu, Wang, Huishan
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436513/
https://ncbi.nlm.nih.gov/pubmed/26074971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/176409
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