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Detection of Plasma Protease Activity Using Microsphere-Cytometry Assays with E. coli Derived Substrates: VWF Proteolysis by ADAMTS13

Protease levels in human blood are often prognostic indicators of inflammatory, thrombotic or oncogenic disorders. The measurement of such enzyme activities in substrate-based assays is complicated due to the low prevalence of these enzymes and steric hindrance of the substrates by the more abundant...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gogia, Shobhit, Lo, Chi Y., Neelamegham, Sriram
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436310/
https://ncbi.nlm.nih.gov/pubmed/25992814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126556
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