RB-pathway Disruption is Associated with Improved Response to Neoadjuvant Chemotherapy in Breast Cancer

PURPOSE: We sought to determine whether dysregulation of the RB tumor suppressor pathway was associated with improved response to neoadjuvant chemotherapy in breast cancer. EXPERIMENTAL DESIGN: An RB-loss signature was used to analyze the association between pathway status and pathological complete...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Witkiewicz, Agnieszka K., Ertel, Adam, McFalls, Jeanne, Valsecchi, Matias E, Schwartz, Gordon, Knudsen, Erik S.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436088/
https://ncbi.nlm.nih.gov/pubmed/22811582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0903
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