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Human Podoplanin-positive Monocytes and Platelets Enhance Lymphangiogenesis Through the Activation of the Podoplanin/CLEC-2 Axis

Emerging studies suggested that murine podoplanin-positive monocytes (PPMs) are involved in lymphangiogenesis. The goal of this study was to demonstrate the therapeutic lymphangiogenesis of human PPMs by the interaction with platelets. Aggregation culture of human peripheral blood mononuclear cells...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: Hur, Jin, Jang, Jae Hee, Oh, Il-Young, Choi, Jae-Il, Yun, Ji-Yeon, Kim, Joonoh, Choi, Young-Eun, Ko, Seung-Bum, Kang, Jin-A, Kang, Jeehoon, Lee, Sang Eun, Lee, Hwan, Park, Young-Bae, Kim, Hyo-Soo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435587/
https://ncbi.nlm.nih.gov/pubmed/24736277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.61
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