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Carbohydrate-binding protein CLEC14A regulates VEGFR-2– and VEGFR-3–dependent signals during angiogenesis and lymphangiogenesis

Controlled angiogenesis and lymphangiogenesis are essential for tissue development, function, and repair. However, aberrant neovascularization is an essential pathogenic mechanism in many human diseases, including diseases involving tumor growth and survival. Here, we have demonstrated that mice def...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Lee, Sungwoon, Rho, Seung-Sik, Park, Hyojin, Park, Jeong Ae, Kim, Jihye, Lee, In-Kyu, Koh, Gou Young, Mochizuki, Naoki, Kim, Young-Myeong, Kwon, Young-Guen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272179/
https://ncbi.nlm.nih.gov/pubmed/27991863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85145
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