Gene Transfer Properties and Structural Modeling of Human Stem Cell-derived AAV

Adeno-associated virus (AAV) vectors are proving to be remarkably successful for in vivo gene delivery. Based upon reports of abundant AAV in the human marrow, we tested CD34(+) hematopoietic stem cells for the presence of natural AAV. Here, we report for the first time, the presence of novel AAV va...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Smith, Laura J, Ul-Hasan, Taihra, Carvaines, Sarah K, Van Vliet, Kim, Yang, Ethel, Wong, Kamehameha K, Agbandje-McKenna, Mavis, Chatterjee, Saswati
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435483/
https://ncbi.nlm.nih.gov/pubmed/24925207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.107
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