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Stem cell-derived clade F AAVs mediate high-efficiency homologous recombination-based genome editing
The precise correction of genetic mutations at the nucleotide level is an attractive permanent therapeutic strategy for human disease. However, despite significant progress, challenges to efficient and accurate genome editing persist. Here, we report a genome editing platform based upon a class of h...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6077703/ https://ncbi.nlm.nih.gov/pubmed/30018062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802343115 |
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