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Stem cell-derived clade F AAVs mediate high-efficiency homologous recombination-based genome editing

The precise correction of genetic mutations at the nucleotide level is an attractive permanent therapeutic strategy for human disease. However, despite significant progress, challenges to efficient and accurate genome editing persist. Here, we report a genome editing platform based upon a class of h...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Smith, Laura J., Wright, Jason, Clark, Gabriella, Ul-Hasan, Taihra, Jin, Xiangyang, Fong, Abigail, Chandra, Manasa, St Martin, Thia, Rubin, Hillard, Knowlton, David, Ellsworth, Jeff L., Fong, Yuman, Wong, Kamehameha K., Chatterjee, Saswati
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077703/
https://ncbi.nlm.nih.gov/pubmed/30018062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802343115
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