Muscular dystrophy in the mdx mouse is a severe myopathy compounded by hypotrophy, hypertrophy and hyperplasia

BACKGROUND: Preclinical testing of potential therapies for Duchenne muscular dystrophy (DMD) is conducted predominantly of the mdx mouse. But lack of a detailed quantitative description of the pathology of this animal limits our ability to evaluate the effectiveness of putative therapies or their re...

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Vydáno v:Skelet Muscle
Hlavní autoři: Duddy, William, Duguez, Stephanie, Johnston, Helen, Cohen, Tatiana V, Phadke, Aditi, Gordish-Dressman, Heather, Nagaraju, Kanneboyina, Gnocchi, Viola, Low, SiewHui, Partridge, Terence
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434871/
https://ncbi.nlm.nih.gov/pubmed/25987977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-015-0041-y
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