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BRG1 Mutations Found in Human Cancer Cell Lines Inactivate Rb-mediated Cell Cycle Arrest

Eukaryotic organisms package DNA into chromatin for compact storage in the cell nucleus. However, this process promotes transcriptional repression of genes. To overcome the transcriptional repression, chromatin remodeling complexes have evolved that alter the configuration of chromatin packaging of...

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Bibliographic Details
Published in:J Cell Physiol
Main Authors: Bartlett, Christopher, Stammler, Tess, Rosson, Gary S., Weissman, Bernard E.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433745/
https://ncbi.nlm.nih.gov/pubmed/21520050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22533
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