BRG-1 is required for RB-mediated cell cycle arrest

The antiproliferative action of the retinoblastoma tumor suppressor protein, RB, is disrupted in the majority of human cancers. Disruption of RB activity occurs through several disparate mechanisms, including viral oncoprotein binding, deregulated RB phosphorylation, and mutation of the RB gene. Her...

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Autors principals: Strobeck, Matthew W., Knudsen, Karen E., Fribourg, Anne F., DeCristofaro, Marc F., Weissman, Bernard E., Imbalzano, Anthony N., Knudsen, Erik S.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC16616/
https://ncbi.nlm.nih.gov/pubmed/10884406
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