SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure

Null mutations in one copy of ATP2A2, the gene encoding sarco/endoplasmic reticulum Ca(2+)-ATPase isoform 2 (SERCA2), cause Darier disease in humans, a skin condition involving keratinocytes. Cardiac function appears to be unimpaired in Darier disease patients, with no evidence that SERCA2 haploinsu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biomed Res Int
Päätekijät: Prasad, Vikram, Lorenz, John N., Lasko, Valerie M., Nieman, Michelle L., Huang, Wei, Wang, Yigang, Wieczorek, David W., Shull, Gary E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433638/
https://ncbi.nlm.nih.gov/pubmed/26064889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/251598
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia