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Decoy receptor DcR1 is induced in a p50/Bcl3-dependent manner and attenuates the efficacy of temozolomide

Temozolomide is used widely to treat malignant glioma but the overall response to this agent is generally poor. Resistance to DNA damaging drugs such as temozolomide has been related to the induction of anti-apoptotic proteins. Specifically, the transcription factor NF-κB has been suggested to parti...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Res
Main Authors: Mansour, Nassir M., Bernal, Giovanna M., Wu, Longtao, Crawley, Clayton D., Cahill, Kirk E., Voce, David J., Balyasnikova, Irina V., Zhang, Wei, Spretz, Ruben, Nunez, Luis, Larsen, Gustavo F., Weichselbaum, Ralph R., Yamini, Bakhtiar
פורמט: Artigo
שפה:Inglês
יצא לאור: 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433625/
https://ncbi.nlm.nih.gov/pubmed/25808868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2144
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