Temozolomide treatment induces lncRNA MALAT1 in an NF-кB and p53 co-dependent manner in glioblastoma

Alkylating chemotherapy is a central component of the management of glioblastoma (GBM). Among the factors that regulate the response to alkylation damage, NF-кB acts to both promote and block cytotoxicity. In this study, we used genome-wide expression analysis in U87 GBM to identify NF-кB-dependent...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Voce, David J., Bernal, Giovanna M., Wu, Longtao, Crawley, Clayton D., Zhang, Wei, Mansour, Nassir M., Cahill, Kirk E., Szymura, Szymon J., Uppal, Abhineet, Raleigh, David R., Spretz, Ruben, Nunez, Luis, Larsen, Gustavo, Khodarev, Nikolai N., Weichselbaum, Ralph R., Yamini, Bakhtiar
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522287/
https://ncbi.nlm.nih.gov/pubmed/30940658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2170
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