Temozolomide treatment induces lncRNA MALAT1 in an NF-кB and p53 co-dependent manner in glioblastoma

Alkylating chemotherapy is a central component of the management of glioblastoma (GBM). Among the factors that regulate the response to alkylation damage, NF-кB acts to both promote and block cytotoxicity. In this study, we used genome-wide expression analysis in U87 GBM to identify NF-кB-dependent...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Voce, David J., Bernal, Giovanna M., Wu, Longtao, Crawley, Clayton D., Zhang, Wei, Mansour, Nassir M., Cahill, Kirk E., Szymura, Szymon J., Uppal, Abhineet, Raleigh, David R., Spretz, Ruben, Nunez, Luis, Larsen, Gustavo, Khodarev, Nikolai N., Weichselbaum, Ralph R., Yamini, Bakhtiar
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522287/
https://ncbi.nlm.nih.gov/pubmed/30940658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2170
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