Decoy receptor DcR1 is induced in a p50/Bcl3-dependent manner and attenuates the efficacy of temozolomide

Temozolomide is used widely to treat malignant glioma but the overall response to this agent is generally poor. Resistance to DNA damaging drugs such as temozolomide has been related to the induction of anti-apoptotic proteins. Specifically, the transcription factor NF-κB has been suggested to parti...

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Publicado no:Cancer Res
Main Authors: Mansour, Nassir M., Bernal, Giovanna M., Wu, Longtao, Crawley, Clayton D., Cahill, Kirk E., Voce, David J., Balyasnikova, Irina V., Zhang, Wei, Spretz, Ruben, Nunez, Luis, Larsen, Gustavo F., Weichselbaum, Ralph R., Yamini, Bakhtiar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433625/
https://ncbi.nlm.nih.gov/pubmed/25808868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2144
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