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BCL3 expression promotes resistance to alkylating chemotherapy in gliomas

The response of patients with gliomas to alkylating chemotherapy is heterogeneous. However, there are currently no universally accepted predictors of patient response to these agents. We identify the nuclear factor κB (NF-κB) co-regulator B cell CLL/lymphoma 3 (BCL-3) as an independent predictor of...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Wu, Longtao, Bernal, Giovanna M., Cahill, Kirk E., Pytel, Peter, Fitzpatrick, Carrie A., Mashek, Heather, Weichselbaum, Ralph R., Yamini, Bakhtiar
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613219/
https://ncbi.nlm.nih.gov/pubmed/29973405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aar2238
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