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Vascular Smooth Muscle Cells Contribute to APOL1-induced Podocyte Injury in HIV milieu

Clinical reports have demonstrated that higher rates of non-diabetic glomerulosclerosis in African Americans can be attributed to two coding sequence variants (G1 and G2) in the APOL1 gene; however, the underlying mechanism is still unknown. Kidney biopsy data suggest enhanced expression of APOL1/AP...

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Detalhes bibliográficos
Publicado no:Exp Mol Pathol
Main Authors: Lan, Xiqian, Wen, Hongxiu, Saleem, Moin A., Mikulak, Joanna, Malhotra, Ashwani, Skorecki, Karl, Singhal, Pravin C
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433601/
https://ncbi.nlm.nih.gov/pubmed/25796344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2015.03.020
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