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Alterations in Plasma Membrane Ion Channel Structures Stimulate NLRP3 Inflammasomes Activation in APOL1 Risk Milieu
We evaluated alterations in the structural configurations of channels and activation of NLRP3 inflammasomes formation in APOL1 risk and non-risk milieus. APOL1G1- and APOL1G2- expressing podocytes displayed enhanced K(+) efflux, induction of pyroptosis, and escalated transcription of interleukin (IL...
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| Publicat a: | FEBS J |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7298666/ https://ncbi.nlm.nih.gov/pubmed/31714001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15133 |
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