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The Michael-type cyclizations in lantibiotic biosynthesis are reversible
Lanthipeptides are members of the ribosomally synthesized and posttranslationally modified peptides (RiPPs). They are generated in two biosynthetic steps, dehydration of Ser and Thr residues to the corresponding dehydroamino acids and subsequent conjugate addition by the thiol of Cys residues to gen...
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| Published in: | ACS Chem Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433588/ https://ncbi.nlm.nih.gov/pubmed/25723375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00007 |
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